Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17756167 | 0.82 | SLC15A1 (0.40) | SYKSLC15A1PPARACA2CA9 | |
| SCHEMBL1704913 | 0.77 | CPA1 (0.60) | SLC15A1CA2CA9SLC1A1SLC1A3 | |
| SCHEMBL1915766 | 0.77 | CPA1 (0.60) | SLC15A1CA2CA9SLC1A1SLC1A3 | |
| SCHEMBL1704171 | 0.77 | CPA1 (0.60) | SLC15A1CA2CA9SLC1A1SLC1A3 | |
| SCHEMBL8879006 | 0.77 | SLC1A1 (0.49) | PPARASLC1A1SLC1A3SLC1A2CYP1A2 | |
| SCHEMBL5492424 | 0.77 | SLC1A1 (0.50) | SYKSLC15A1PPARACA2CA9 | |
| SCHEMBL2410585 | 0.76 | PPARA (0.49) | SLC15A1PPARACA2CA9SLC1A1 | |
| SCHEMBL2410580 | 0.76 | PPARA (0.49) | SLC15A1PPARACA2CA9SLC1A1 | |
| SCHEMBL17756152 | 0.76 | PPARA (0.49) | SLC15A1PPARACA2CA9SLC1A1 | |
| SCHEMBL8092700 | 0.76 | PPARA (0.41) | SYKPPARASLC1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821666-B1 | DERIVATIVES OF SUCCINAMIDE AND THEIR USE AS METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 2000-12-27 | — | — | EP | disclosed |
| US-5840939-A | Derivatives of succinamide and their use as metalloproteinase inhibitors | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 1998-11-24 | — | — | US | disclosed |