SCHEMBL809279

SCHEMBL809279

CC(C)(C)C(c1ccc(O)cc1)C(C)(C)C(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.44
ESR2 Q92731 9/20 0.44
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
CYP3A4 P08684 4/20 0.40
LMNA P02545 3/20 0.40
AR P10275 2/20 0.40
SLC6A2 P23975 2/20 0.40
SLC6A3 Q01959 2/20 0.40
CYP2C9 P11712 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 2/20 0.40
ALOX15 P16050 2/20 0.40
CYP1A2 P05177 1/20 0.40
PGR P06401 1/20 0.40
CHRM2 P08172 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CYP2D6 P10635 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD1 P21728 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL301927 0.86 ESR1 (0.52) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL14014347 0.77 ESR1 (0.48) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL10339282 0.74 ESR1 (0.50) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL23729016 0.73 SHBG (0.39) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL5457267 0.72 ESR1 (0.61) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL8751432 0.70 ESR1 (0.56) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL15932252 0.70 ESR1 (0.50) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL14411802 0.70 ESR1 (0.56) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL2452815 0.70 ESR1 (0.50) ESR1ESR2PDCD1CD274CYP3A4
SCHEMBL9812323 0.68 ESR1 (0.50) ESR1ESR2PDCD1CD274CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1483317-B1 LOW YELLOWING SCORCH INHIBITOR COMPOSITION VANDERBILT CO R T (US) 2011-11-23 EP claimed
JP-4154339-B2 2008-09-24 JP claimed
JP-2005520026-A 2005-07-07 JP claimed
EP-1483317-A1 LOW YELLOWING SCORCH INHIBITOR COMPOSITION R.T. VANDERBILT COMPANY, INC. (US) 2004-12-08 EP claimed
US-6676849-B2 Comprises 4-tert-butyl-4-isobutyl phenol, 4-tert-butyl catechol, and phenothiazine, for preventing discoloration due to exposure to nitrogen oxides, ultraviolet radiation, and fluorescent light during production of polyurethane foams R. T. VANDERBILT COMPANY, INC. 2004-01-13 US claimed
US-20030199598-A1 Low yellowing scorch inhibitor composition R.T. VANDERBILT COMPANY, INC. 2003-10-23 US claimed
WO-2003078515-A1 LOW YELLOWING SCORCH INHIBITOR COMPOSITION R.T. VANDERBILT COMPANY INC. (US) 2003-09-25 WO claimed
EP-1483317-B1 LOW YELLOWING SCORCH INHIBITOR COMPOSITION VANDERBILT CO R T (US) 2011-11-23 EP disclosed
EP-1483317-B1 LOW YELLOWING SCORCH INHIBITOR COMPOSITION VANDERBILT CO R T (US) 2011-11-23 EP disclosed
CN-1274742-C Low yellowing scorch inhibitor composition VANDERBILT CO R T (US) 2006-09-13 CN disclosed
CN-1639242-A Low yellowing scorch inhibitor composition VANDERBILT CO R T (US) 2005-07-13 CN disclosed
EP-1483317-A1 LOW YELLOWING SCORCH INHIBITOR COMPOSITION R.T. VANDERBILT COMPANY, INC. (US) 2004-12-08 EP disclosed
EP-1483317-A1 LOW YELLOWING SCORCH INHIBITOR COMPOSITION R.T. VANDERBILT COMPANY, INC. (US) 2004-12-08 EP disclosed
US-6676849-B2 Comprises 4-tert-butyl-4-isobutyl phenol, 4-tert-butyl catechol, and phenothiazine, for preventing discoloration due to exposure to nitrogen oxides, ultraviolet radiation, and fluorescent light during production of polyurethane foams R. T. VANDERBILT COMPANY, INC. 2004-01-13 US disclosed
US-6676849-B2 Comprises 4-tert-butyl-4-isobutyl phenol, 4-tert-butyl catechol, and phenothiazine, for preventing discoloration due to exposure to nitrogen oxides, ultraviolet radiation, and fluorescent light during production of polyurethane foams R. T. VANDERBILT COMPANY, INC. 2004-01-13 US disclosed
US-20030199598-A1 Low yellowing scorch inhibitor composition R.T. VANDERBILT COMPANY, INC. 2003-10-23 US disclosed
US-20030199598-A1 Low yellowing scorch inhibitor composition R.T. VANDERBILT COMPANY, INC. 2003-10-23 US disclosed
WO-2003078515-A1 LOW YELLOWING SCORCH INHIBITOR COMPOSITION R.T. VANDERBILT COMPANY INC. (US) 2003-09-25 WO disclosed
WO-2003078515-A1 LOW YELLOWING SCORCH INHIBITOR COMPOSITION R.T. VANDERBILT COMPANY INC. (US) 2003-09-25 WO disclosed