Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM6A | O15550 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | INMT | O95050 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15417770 | 0.83 | CA12 (0.47) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL15100188 | 0.71 | PDE4A (0.32) | — | |
| SCHEMBL1768217 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL13386456 | 0.70 | CA12 (0.57) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL9705983 | 0.69 | AKR1B1 (0.49) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL6628483 | 0.69 | — | — | |
| SCHEMBL2606749 | 0.69 | — | — | |
| SCHEMBL17233960 | 0.69 | — | — | |
| Glycerin SCHEMBL6955459 | 0.68 | CA12 (0.46) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL14245146 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36831-E | TREATMENT OF IRON DEFICIENCY ANEMIA | BRITISH TECHNOLOGY GROUP LTD. (GB) | 2000-08-22 | — | — | US | disclosed |
| US-RE35948-E | TREATING TOXIC METAL CONCENTRATION BY ADMINISTERING N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR 3-HYDROXYPYRID-4-ONE | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1998-11-03 | — | — | US | disclosed |
| EP-0305646-A2 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1989-03-08 | — | — | EP | disclosed |
| US-4650793-A | NITROGEN-SUBSTITUTED | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-17 | — | — | US | disclosed |
| US-4585780-A | CHELATION OF HEAVY METALS IN BLOOD | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-04-29 | — | — | US | disclosed |