Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14461952 | 0.88 | GABRA1 (0.48) | GABRA1GABRB2HKDC1SIRT1CYP2C9 | |
| SCHEMBL21547612 | 0.87 | GABRA1 (0.38) | GABRA1GABRB2HKDC1LMNASIRT1 | |
| SCHEMBL25636439 | 0.82 | KDM4E (0.39) | HKDC1LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL9174672 | 0.82 | TYR (0.42) | HKDC1PTGESALOX5CYP2C9CYP3A4 | |
| SCHEMBL3325227 | 0.81 | ESR1 (0.44) | HKDC1LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL28888530 | 0.81 | SLC6A2 (0.38) | HKDC1LMNAPTGESALOX5HDAC1 | |
| SCHEMBL28252384 | 0.81 | HTT (0.40) | LMNAHDAC1HDAC8HDAC6SLC6A2 | |
| SCHEMBL5011788 | 0.81 | HTT (0.40) | LMNAHDAC1HDAC8HDAC6SLC6A2 | |
| SCHEMBL20683924 | 0.80 | PRKCE (0.41) | HKDC1LMNAHSD17B10SLC6A2SLC6A4 | |
| SCHEMBL17356541 | 0.79 | PRKCE (0.40) | GABRA1GABRB2LMNASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114487-A | COATING AGENT, MOLDING MATERIAL, IMPROVED MOLD RELEASE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2000-09-05 | — | — | US | disclosed |