Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 14/20 | 0.67 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.67 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.67 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.65 |
| ▸ | HTR3B | O95264 | 1/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | HTR1D | P28221 | 1/20 | 0.65 |
| ▸ | HTR1B | P28222 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
| ▸ | HTR1E | P28566 | 1/20 | 0.65 |
| ▸ | HTR1F | P30939 | 1/20 | 0.65 |
| ▸ | HTR7 | P34969 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | HTR3A | P46098 | 1/20 | 0.65 |
| ▸ | HTR5A | P47898 | 1/20 | 0.65 |
| ▸ | HTR6 | P50406 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357751 | 0.91 | OXTR (0.77) | OXTRAVPR2AVPR1AHTR3EHTR3B | |
| SCHEMBL8089301 | 0.89 | OXTR (0.85) | OXTRAVPR2AVPR1AHTR3EHTR3B | |
| SCHEMBL8089420 | 0.89 | OXTR (0.81) | OXTRAVPR2AVPR1AHTR3EHTR3B | |
| SCHEMBL8081328 | 0.84 | OXTR (0.76) | OXTRAVPR2AVPR1AHTR3EHTR3B | |
| SCHEMBL8089362 | 0.82 | OXTR (0.69) | OXTRAVPR2AVPR1AHTR3EHTR3B | |
| SCHEMBL8081347 | 0.82 | OXTR (0.75) | OXTRAVPR2AVPR1AHTR3EHTR3B | |
| SCHEMBL8081394 | 0.80 | OXTR (1.00) | OXTRAVPR2AVPR1AHTR3EHTR3B | |
| SCHEMBL8088568 | 0.80 | OXTR (0.77) | OXTRAVPR2AVPR1AHTR3EHTR3B | |
| SCHEMBL7446609 | 0.80 | OXTR (0.62) | OXTRAVPR2AVPR1A | |
| SCHEMBL7357703 | 0.80 | OXTR (0.82) | OXTRAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090805-A | Tocolytic oxytocin receptor antagonists | MERCK & CO., INC. (US) | 2000-07-18 | — | — | US | disclosed |