SCHEMBL809303

SCHEMBL809303

C=CC(CCC)OC(=O)C(=C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TSHR P16473 4/20 0.38
THRB P10828 1/20 0.35
CHRM1 P11229 1/20 0.30
AKR1A1 P14550 1/20 0.30
CHRM3 P20309 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30
HRH1 P35367 1/20 0.30
DRD3 P35462 1/20 0.30
SLC6A3 Q01959 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC2 Q92769 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809078 0.88 TSHR (0.46) TSHR
SCHEMBL809013 0.86 TSHR (0.49) TSHR
SCHEMBL28104274 0.85 TSHR (0.39) ALDH1A1TSHRTHRB
SCHEMBL2850328 0.82 TSHR (0.36) ALDH1A1TSHRCHRM1AKR1A1CHRM3
SCHEMBL899428 0.82 TSHR (0.35) ALDH1A1TSHRTHRB
Bicarbonate SCHEMBL27518089 0.81 TSHR (0.37) ALDH1A1TSHRTHRB
SCHEMBL4799744 0.81 TSHR (0.39) ALDH1A1TSHRTHRB
SCHEMBL29098264 0.81 TSHR (0.39) ALDH1A1TSHRTHRB
SCHEMBL20819794 0.81 THRB (0.36) ALDH1A1TSHRTHRB
SCHEMBL5708594 0.80 TSHR (0.37) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1942508-B Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORP 2011-05-11 CN claimed
US-7727679-B2 Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORPORATION (JP) 2010-06-01 US claimed
CN-110891981-A Radiation curable coating composition for improving surface properties of plastics 阿科玛法国公司 2020-03-17 CN disclosed
EP-1834977-B1 OPTICAL REFRACTIVE INDEX-MODIFYING POLYMER COMPOSITION, HOLOGRAPHIC RECORDING MATERIAL AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORP (JP) 2013-08-21 EP disclosed
EP-1669378-B1 LIGHT REFRACTIVE INDEX MODULATION POLYMER COMPOSITION AND METHOD OF CONTROLLING REFRACTIVE INDEX NITTO DENKO CORP (JP) 2012-01-18 EP disclosed
CN-1942508-B Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORP 2011-05-11 CN disclosed
CN-101061442-B Hologram recording material NITTO DENKO CORP 2011-02-02 CN disclosed
US-7781124-B2 Hologram recording material NITTO DENKO CORPORATION (JP) 2010-08-24 US disclosed
US-7727679-B2 Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORPORATION (JP) 2010-06-01 US disclosed
US-7566745-B2 Photochemically refractive-index-changing polymer, photochemically refractive-index-changing polymer composition, and method of refractive index regulation NITTO DENKO CORPORATION (JP) 2009-07-28 US disclosed
US-20080305404-A1 Which can vary refractive index upon irradiation with visible light laser and exhibits an excellent transparency after the modulation without requiring any conventional complicated procedure; syndiotactic acrylic ester polymer with side chain vinyl group, and specific photopolymerization initiator NITTO DENKO CORPORATION (JP) 2008-12-11 US disclosed
US-20070128523-A1 Optical refractive index-modifying polymer composition, hologram recording material and method of controlling refractive index NITTO DENKO CORPORATION (JP) 2007-06-07 US disclosed
US-20070066705-A1 Photochemically refractive-index-changing polymer, photochemically refractive-index-changing polymer composition, and method of refractive index regulation NITTO DENKO CORPORATION (JP) 2007-03-22 US disclosed
CN-1863829-A Optical refractive index modulation polymer, optical refractive index modulation polymer composition, and refractive index adjustment method NITTO DENKO CORP (JP) 2006-11-15 CN disclosed
CN-1105520-C Clothing bearing retroreflective appliques MINNESOTA MINING & MFG (US) 2003-04-16 CN disclosed
CN-1144462-A Clothing bearing retroreflective appliques MINNESOTA MINING & MFG (US) 1997-03-05 CN disclosed
US-5210301-A Compounds for charge generating layers FUJI XEROX CO., LTD. (JP) 1993-05-11 US disclosed
EP-0161005-B1 NOVEL SQUARIUM COMPOUNDS, PROCESS FOR PREPARING THE SAME AND ELECTROPHOTOGRAPHIC PHOTORECEPTORS CONTAINING THE SAME FUJI XEROX CO., LTD. (JP) 1989-12-20 EP disclosed
US-4626485-A Substituted squarium compounds, process for preparing the same and electrophotographic photoreceptors containing the same FUJI XEROX CO., LTD. (JP) 1986-12-02 US disclosed
EP-0161005-A2 Novel squarium compounds, process for preparing the same and electrophotographic photoreceptors containing the same FUJI XEROX CO., LTD. (JP) 1985-11-13 EP disclosed