⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086833 | 1.00 | — | — | |
| SCHEMBL12274088 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL27561172 | 0.97 | INPP5A (0.35) | — | |
| SCHEMBL27985468 | 0.97 | — | — | |
| Ammonia Solution, Strong SCHEMBL12274377 | 0.97 | — | — | |
| SCHEMBL6440603 | 0.97 | — | — | |
| SCHEMBL27499950 | 0.83 | SUCNR1 (0.46) | — | |
| SCHEMBL28479003 | 0.82 | CHRM2 (0.42) | — | |
| SCHEMBL4017162 | 0.82 | CHRM2 (0.42) | — | |
| SCHEMBL28481165 | 0.82 | CHRM2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485894-B1 | Methods for the preparation of semi-synthetic diastereomerically pure N-glycidyl-anthracyclines | HOECHST AG (DE) | 1999-02-03 | — | — | EP | claimed |
| EP-0485894-A1 | Semi-synthetic diastereomerically pure N-glycidyl-anthracyclines, methods for their preparation, and their use as cytostatics | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-05-20 | — | — | EP | claimed |
| JP-4330036-A | — | — | None | — | — | JP | disclosed |
| CN-108702971-A | A kind of automation nutrition spray appliance | 金华市鸿讯机械工程技术有限公司 | 2018-10-26 | — | — | CN | disclosed |
| CN-108651066-A | A kind of automatic shield flower flower pot arrangement | 金华市泉宇科技有限公司 | 2018-10-16 | — | — | CN | disclosed |
| US-9133143-B2 | (3-fluoro-2-hydroxy)propyl-functionalized aryl derivatives or pharmaceutically acceptable salts thereof, method for preparing same, and pharmaceutical composition containing same as active ingredient for the diagnosis or treatment of neurodegenerative brain diseases | FUTURECHEM CO., LTD. (KR) | 2015-09-15 | — | — | US | disclosed |
| US-20120214994-A1 | (3-FLUORO-2-HYDROXY)PROPYL-FUNCTIONALIZED ARYL DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR THE DIAGNOSIS OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASES | FUTURECHEM CO., LTD. (KR) | 2012-08-23 | — | — | US | disclosed |
| EP-0884313-B1 | PROCESS FOR PRODUCING GLYCIDYL SULFONATE DERIVATIVES | DAISO CO LTD (JP) | 2000-11-08 | — | — | EP | disclosed |
| US-5965753-A | Process for preparation of glycidyl sulfonate derivative | DAISO CO., LTD. (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0485894-B1 | Methods for the preparation of semi-synthetic diastereomerically pure N-glycidyl-anthracyclines | HOECHST AG (DE) | 1999-02-03 | — | — | EP | disclosed |
| EP-0884313-A1 | PROCESS FOR PRODUCING GLYCIDYL SULFONATE DERIVATIVES | DAISO CO., LTD. (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5602108-A | Semisynthetic diastereomerically pure N-glycidylanthracyclines, a process for the stereoselective preparation thereof as the use thereof as cytostatics | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5602108-A | Semisynthetic diastereomerically pure N-glycidylanthracyclines, a process for the stereoselective preparation thereof as the use thereof as cytostatics | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| JP-H04330036-A | SEMISYNTHETIC N-GLYCIDYLANTHRACYCLINE WHICH IS DIASTEREOTOPCALLY PURE, ITS STERIC SELECTIVE PRODUCTION AND ITS USE AS INHIBITOR AGAINST CELL GROWTH | BEHRINGWERKE AG | 1992-11-18 | — | — | JP | disclosed |
| EP-0485894-A1 | Semi-synthetic diastereomerically pure N-glycidyl-anthracyclines, methods for their preparation, and their use as cytostatics | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-05-20 | — | — | EP | disclosed |
| EP-0485894-A1 | Semi-synthetic diastereomerically pure N-glycidyl-anthracyclines, methods for their preparation, and their use as cytostatics | BEHRINGWERKE Aktiengesellschaft (DE) | 1992-05-20 | — | — | EP | disclosed |