Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.51 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BID | P55957 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101352 | 0.98 | HTR2A (0.52) | HTR2ATLR8LIPGKCNH2SIGMAR1 | |
| SCHEMBL8094124 | 0.98 | HTR2A (0.52) | HTR2ATLR8LIPGKCNH2SIGMAR1 | |
| SCHEMBL8094855 | 0.98 | HTR2A (0.52) | HTR2ATLR8LIPGKCNH2SIGMAR1 | |
| SCHEMBL22471642 | 0.96 | HTR2A (0.57) | HTR2ATLR8LIPGKCNH2SIGMAR1 | |
| SCHEMBL27342279 | 0.94 | HTR2A (0.55) | HTR2ATLR8LIPGKCNH2SIGMAR1 | |
| SCHEMBL22471644 | 0.94 | HTR2A (0.55) | HTR2ATLR8LIPGKCNH2SIGMAR1 | |
| SCHEMBL10454636 | 0.94 | HTR2A (0.55) | HTR2ATLR8LIPGKCNH2SIGMAR1 | |
| SCHEMBL8093734 | 0.94 | HTR2A (0.55) | HTR2ATLR8LIPGSIGMAR1CALM1 | |
| SCHEMBL8086301 | 0.94 | LIPG (0.53) | HTR2ATLR8LIPGLMNABID | |
| SCHEMBL8098698 | 0.92 | LIPG (0.56) | HTR2ATLR8LIPGKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |