Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.50 |
| ▸ | RARG | P13631 | 5/20 | 0.50 |
| ▸ | RARA | P10276 | 4/20 | 0.48 |
| ▸ | RXRA | P19793 | 13/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | RXRB | P28702 | 7/20 | 0.43 |
| ▸ | RXRG | P48443 | 7/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6733785 | 0.91 | RXRA (0.46) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL7801892 | 0.87 | RXRA (0.58) | RARBRARGRARARXRARXRB | |
| SCHEMBL6734636 | 0.84 | CYP3A4 (0.51) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL16744298 | 0.79 | RARB (0.73) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL6734814 | 0.78 | RXRA (0.58) | RARBRARGRARARXRARXRB | |
| SCHEMBL29595859 | 0.77 | RARB (0.52) | RARBRARGRARAALDH1A1TSHR | |
| SCHEMBL20887637 | 0.77 | RARB (0.52) | RARBRARGRARAALDH1A1TSHR | |
| SCHEMBL8101333 | 0.77 | RARB (0.47) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL7771646 | 0.76 | RXRA (0.41) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL7801865 | 0.76 | RXRA (0.39) | RARBRARGRARARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030952-A | AS HUMAN AND VETERINARY MEDICINE, PARTICULARLY IN THE TREATMENT OF DERMATOLOGICAL, RHEUMATIC, RESPIRATORY, CARDIOVASCULAR AND OPHTHALMOLOGIC CONDITIONS, AND IN COSMETIC COMPOSITIONS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIOUES GALDERMA (FR) | 2000-02-29 | — | — | US | disclosed |