Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27462087 | 1.00 | HDAC1 (0.44) | HDAC1HDAC8HDAC6ELANEFKBP1A | |
| SCHEMBL8093325 | 1.00 | HDAC1 (0.44) | HDAC1HDAC8HDAC6ELANEFKBP1A | |
| SCHEMBL17138602 | 0.85 | ELANE (0.46) | HDAC1HDAC8HDAC6ELANEALDH1A1 | |
| SCHEMBL28613404 | 0.84 | ALDH1A1 (0.47) | HDAC1HDAC8HDAC6ELANEALDH1A1 | |
| SCHEMBL7779876 | 0.82 | HDAC1 (0.46) | HDAC1HDAC8HDAC6ELANEALDH1A1 | |
| SCHEMBL7780936 | 0.82 | HDAC1 (0.46) | HDAC1HDAC8HDAC6ELANEALDH1A1 | |
| SCHEMBL7779878 | 0.82 | HDAC1 (0.46) | HDAC1HDAC8HDAC6ELANEALDH1A1 | |
| SCHEMBL7782731 | 0.82 | HDAC1 (0.46) | HDAC1HDAC8HDAC6ELANEALDH1A1 | |
| SCHEMBL7775653 | 0.82 | HDAC1 (0.46) | HDAC1HDAC8HDAC6ELANEALDH1A1 | |
| SCHEMBL9393124 | 0.80 | HDAC1 (0.43) | HDAC1HDAC8HDAC6FKBP1AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140510-A | Optically active 3-(1-(carbamoyl))alkyl-2-oxo-pyrrolidines and optically active 3-(1-(alkylamido))alkyl-2-oxo-pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-31 | — | — | US | disclosed |
| US-5962697-A | Optically active 3-(1-(alkylamino))alkyl pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| US-5773610-A | Optically active 3-(1-(alkylamino))alkyl pyrrolidines | PHARMACIA & UPJOHN COMPANY (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1994026708-A1 | OPTICALLY ACTIVE 3-(1-(ALKYLAMINO))ALKYL PYRROLIDINES | THE UPJOHN COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |