Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 12/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | GC | P02774 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8527156 | 1.00 | CDC25A (0.42) | CDC25ACDC25BVDRMAPTSMN1; SMN2 | |
| SCHEMBL28733909 | 0.95 | CDC25A (0.47) | CDC25ACDC25BVDRMAPTSMN1; SMN2 | |
| SCHEMBL14489088 | 0.95 | CDC25A (0.47) | CDC25ACDC25BVDRMAPTSMN1; SMN2 | |
| SCHEMBL14489129 | 0.95 | CDC25A (0.47) | CDC25ACDC25BVDRMAPTSMN1; SMN2 | |
| SCHEMBL4164697 | 0.95 | CDC25A (0.47) | CDC25ACDC25BVDRMAPTSMN1; SMN2 | |
| SCHEMBL14112463 | 0.87 | CDC25A (0.46) | CDC25ACDC25BVDRMAPTSMN1; SMN2 | |
| SCHEMBL3220674 | 0.85 | CDC25A (0.37) | CDC25ACDC25BVDRMAPTSMN1; SMN2 | |
| SCHEMBL13392704 | 0.85 | CDC25A (0.37) | CDC25ACDC25BVDRMAPTSMN1; SMN2 | |
| SCHEMBL7615044 | 0.85 | CDC25A (0.37) | CDC25ACDC25BVDRMAPTSMN1; SMN2 | |
| SCHEMBL8505239 | 0.85 | VDR (0.55) | VDRMAPTSMN1; SMN2SREBF1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771789-B1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | HOFFMANN LA ROCHE (CH) | 2000-02-16 | — | — | EP | disclosed |
| EP-0771789-A1 | 1 alpha, 26-dihydroxy-D-homo-vitamin D3 | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-07 | — | — | EP | disclosed |