Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689630 | 1.00 | CYP3A4 (0.58) | CYP3A4CNR1CNR2PRSS1PRSS2 | |
| SCHEMBL688275 | 1.00 | CYP3A4 (0.58) | CYP3A4CNR1CNR2PRSS1PRSS2 | |
| SCHEMBL689823 | 0.98 | CYP3A4 (0.59) | CYP3A4CNR1CNR2PRSS1PRSS2 | |
| SCHEMBL17200765 | 0.94 | CYP3A4 (0.51) | CYP3A4CNR1CNR2PRSS1PRSS2 | |
| SCHEMBL3166149 | 0.94 | CYP3A4 (0.51) | CYP3A4CNR1CNR2PRSS1PRSS2 | |
| SCHEMBL9716546 | 0.92 | KMT2A (0.56) | CYP3A4KMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL32684489 | 0.92 | KMT2A (0.56) | CYP3A4KMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL9538006 | 0.92 | KMT2A (0.56) | CYP3A4KMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL6139167 | 0.92 | KMT2A (0.56) | CYP3A4KMT2AMEN1ALDH1A1MAPK1 | |
| SCHEMBL27705782 | 0.92 | CYP3A4 (0.53) | CYP3A4CNR1CNR2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9464183-B2 | Rubber composition and pneumatic tire using the same | BRIDGESTONE CORPORATION (JP) | 2016-10-11 | — | — | US | disclosed |
| EP-1724302-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2011-07-20 | — | — | EP | disclosed |
| US-20110146886-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING THE SAME | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |
| US-20080047650-A1 | Rubber Composition And Pneumatic Tire Using The Same | BRIDGESTONE CORPORATION (JP) | 2008-02-28 | — | — | US | disclosed |
| EP-1724302-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE USING SAME | Bridgestone Corporation (JP) | 2006-11-22 | — | — | EP | disclosed |