Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3166149 | 1.00 | CYP3A4 (0.51) | CYP3A4CNR2CNR1PRSS1PRSS2 | |
| SCHEMBL27705782 | 0.98 | CYP3A4 (0.53) | CYP3A4CNR2CNR1PRSS1PRSS2 | |
| SCHEMBL2845775 | 0.95 | CYP3A4 (0.53) | CYP3A4CNR2CNR1PRSS1PRSS2 | |
| SCHEMBL927349 | 0.94 | CYP3A4 (0.46) | CYP3A4CNR2CNR1PRSS1PRSS2 | |
| SCHEMBL927430 | 0.94 | CYP3A4 (0.46) | CYP3A4CNR2CNR1PRSS1PRSS2 | |
| SCHEMBL688275 | 0.94 | CYP3A4 (0.58) | CYP3A4CNR2CNR1PRSS1PRSS2 | |
| SCHEMBL689630 | 0.94 | CYP3A4 (0.58) | CYP3A4CNR2CNR1PRSS1PRSS2 | |
| SCHEMBL809344 | 0.94 | CYP3A4 (0.58) | CYP3A4CNR2CNR1PRSS1PRSS2 | |
| SCHEMBL928867 | 0.93 | CYP3A4 (0.47) | CYP3A4CNR2CNR1PRSS1PRSS2 | |
| SCHEMBL689823 | 0.92 | CYP3A4 (0.59) | CYP3A4CNR2CNR1PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134062-B1 | COSMETIC COMPOSITIONS HAVING REDUCED IRRITATION | PROCTER & GAMBLE (US) | 2019-09-04 | — | — | EP | disclosed |
| EP-3134062-A1 | COSMETIC COMPOSITIONS HAVING REDUCED IRRITATION | The Procter & Gamble Company (US) | 2017-03-01 | — | — | EP | disclosed |
| US-9480634-B2 | Cosmetic compositions | THE PROCTER & GAMBLE COMPANY (US) | 2016-11-01 | — | — | US | disclosed |
| WO-2015164290-A1 | COSMETIC COMPOSITIONS HAVING REDUCED IRRITATION | THE PROCTER & GAMBLE COMPANY (US) | 2015-10-29 | — | — | WO | disclosed |
| US-20150305994-A1 | Cosmetic Compositions | THE PROCTER & GAMBLE COMPANY | 2015-10-29 | — | — | US | disclosed |
| CN-101076457-B | Pneumatic tire | BRIDGESTONE CORP | 2011-07-27 | — | — | CN | disclosed |
| CN-101076457-A | Pneumatic tire | BRIDGESTONE CORP (JP) | 2007-11-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150305994-A1 | Cosmetic Compositions | FHIT, UGCG, TYR | CYP3A4 1529/4885CNR2 633/4885CNR1 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.