Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 3/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095230 | 0.92 | DUSP3 (0.67) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL8096406 | 0.88 | DUSP3 (0.72) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL8095923 | 0.87 | NPSR1 (0.53) | DUSP3CHRM4TP53LMNACASP3 | |
| SCHEMBL8094946 | 0.87 | DUSP3 (0.55) | DUSP3CHRM4TP53LMNAMEN1 | |
| SCHEMBL8099763 | 0.85 | DUSP3 (0.68) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL8095592 | 0.84 | DUSP3 (0.67) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL3054015 | 0.83 | DUSP3 (0.76) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL8101770 | 0.83 | NPC1 (0.61) | TP53CASP3SENP8SENP6MEN1 | |
| SCHEMBL14807633 | 0.81 | DUSP3 (0.82) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL3045307 | 0.81 | DUSP3 (0.82) | DUSP3CHRM4DYRK1ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604657-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-01-12 | — | — | EP | claimed |
| US-5376665-A | Antidiabetic agent, hypoglycemic agent | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1994-12-27 | — | — | US | claimed |
| EP-0604657-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1994-07-06 | — | — | EP | claimed |
| EP-0604657-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5376665-A | Antidiabetic agent, hypoglycemic agent | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0604657-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1994-07-06 | — | — | EP | disclosed |