Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 4/20 | 0.55 |
| ▸ | SCD | O00767 | 12/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087171 | 0.88 | DUSP3 (0.58) | DUSP3SCDNPC1MEN1RAB9A | |
| SCHEMBL8093460 | 0.87 | DUSP3 (0.67) | DUSP3NPC1MEN1RAB9AKMT2A | |
| SCHEMBL8100073 | 0.80 | DUSP3 (0.55) | DUSP3SCDNPC1MEN1RAB9A | |
| SCHEMBL8095230 | 0.79 | DUSP3 (0.67) | DUSP3NPC1MEN1RAB9AKMT2A | |
| SCHEMBL8095688 | 0.79 | HDAC1 (0.41) | DUSP3SCDNPC1MEN1RAB9A | |
| SCHEMBL8095923 | 0.78 | NPSR1 (0.53) | DUSP3SCDNPC1MEN1RAB9A | |
| SCHEMBL8101770 | 0.77 | NPC1 (0.61) | SCDNPC1MEN1RAB9AKMT2A | |
| SCHEMBL8096406 | 0.74 | DUSP3 (0.72) | DUSP3NPC1MEN1RAB9AKMT2A | |
| SCHEMBL8099763 | 0.74 | DUSP3 (0.68) | DUSP3SCDNPC1MEN1RAB9A | |
| SCHEMBL8095592 | 0.73 | DUSP3 (0.67) | DUSP3SCDNPC1MEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604657-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-01-12 | — | — | EP | claimed |
| EP-0604657-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1994-07-06 | — | — | EP | claimed |