Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP3 | P51452 | 3/20 | 0.69 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.66 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100073 | 0.86 | DUSP3 (0.55) | DUSP3CHRM4TP53LMNAMEN1 | |
| SCHEMBL8096406 | 0.82 | DUSP3 (0.72) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL14807633 | 0.82 | DUSP3 (0.82) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL3045307 | 0.81 | DUSP3 (0.82) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL8095230 | 0.81 | DUSP3 (0.67) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL3054015 | 0.80 | DUSP3 (0.76) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL8093460 | 0.79 | DUSP3 (0.67) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL8099763 | 0.76 | DUSP3 (0.68) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL3311681 | 0.76 | DUSP3 (0.69) | DUSP3CHRM4DYRK1ATP53LMNA | |
| SCHEMBL8095592 | 0.76 | DUSP3 (0.67) | DUSP3CHRM4DYRK1ATP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604657-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2000-01-12 | — | — | EP | claimed |