Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.45 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095531 | 0.98 | ALDH1A1 (0.43) | ALDH1A1ASAH1ACER2HTR2ACSNK1E | |
| SCHEMBL8101515 | 0.92 | POLB (0.47) | ALDH1A1ASAH1ACER2HTR2ASIGMAR1 | |
| SCHEMBL30040284 | 0.85 | ASAH1 (0.45) | ALDH1A1ASAH1ACER2HTR2ACSNK1E | |
| SCHEMBL6284810 | 0.84 | AOC3 (0.44) | ALDH1A1HTR2ASIGMAR1POLBOPRM1 | |
| SCHEMBL28821662 | 0.81 | ALDH1A1 (0.43) | ALDH1A1ASAH1ACER2HTR2ACSNK1E | |
| SCHEMBL28829356 | 0.81 | CSNK1E (0.47) | ALDH1A1ASAH1ACER2HTR2ACSNK1E | |
| SCHEMBL6685005 | 0.81 | ALDH1A1 (0.57) | ALDH1A1ASAH1ACER2HTR2ACSNK1E | |
| SCHEMBL27261976 | 0.81 | ALDH1A1 (0.57) | ALDH1A1ASAH1ACER2HTR2ACSNK1E | |
| SCHEMBL6366902 | 0.81 | CSNK1E (0.47) | ALDH1A1ASAH1ACER2HTR2ACSNK1E | |
| SCHEMBL26113190 | 0.81 | CSNK1E (0.47) | ALDH1A1ASAH1ACER2HTR2ACSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |