Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 4/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087187 | 1.00 | CNR1 (0.39) | CNR1CNR2CYP19A1SLC6A3HRH1 | |
| SCHEMBL8095083 | 0.94 | CNR1 (0.42) | CNR1CNR2CYP19A1SLC6A3HRH1 | |
| SCHEMBL6130573 | 0.94 | CNR1 (0.42) | CNR1CNR2CYP19A1SLC6A3HRH1 | |
| SCHEMBL48724 | 0.89 | MAPT (0.42) | CNR1CNR2CYP19A1CYP17A1TDP1 | |
| SCHEMBL8100164 | 0.89 | MAPT (0.42) | CNR1CNR2CYP19A1CYP17A1TDP1 | |
| SCHEMBL2914007 | 0.89 | MAPT (0.42) | CNR1CNR2CYP19A1CYP17A1TDP1 | |
| SCHEMBL8100949 | 0.88 | CYP19A1 (0.44) | CNR1CNR2CYP19A1SLC6A3HRH1 | |
| SCHEMBL8098344 | 0.88 | CYP19A1 (0.44) | CNR1CNR2CYP19A1SLC6A3HRH1 | |
| Benzene SCHEMBL28278798 | 0.87 | TSHR (0.41) | CNR1CNR2HRH1HTR2ACYP17A1 | |
| SCHEMBL8096162 | 0.86 | CYP19A1 (0.43) | CNR1CNR2CYP19A1HRH1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |