Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6148751 | 0.85 | KMT2A (0.63) | POLBATMKMT2AADRB2MEN1 | |
| SCHEMBL27535388 | 0.85 | KMT2A (0.63) | POLBATMKMT2AADRB2MEN1 | |
| SCHEMBL557799 | 0.83 | ATM (1.00) | POLBATMKMT2AALDH1A1CYP1A2 | |
| SCHEMBL8635081 | 0.83 | ATM (1.00) | POLBATMKMT2AALDH1A1CYP1A2 | |
| SCHEMBL30230461 | 0.83 | ATM (1.00) | POLBATMKMT2AALDH1A1CYP1A2 | |
| SCHEMBL8093689 | 0.82 | KMT2A (0.53) | KMT2AADRB2MEN1 | |
| Iodide SCHEMBL8828192 | 0.81 | ATM (0.96) | POLBATMKMT2AALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3657276 | 0.81 | ATM (0.96) | POLBATMKMT2AALDH1A1CYP1A2 | |
| SCHEMBL6094349 | 0.77 | ADRB2 (0.74) | POLBATMKMT2AADRB2MEN1 | |
| SCHEMBL6094272 | 0.77 | ADRB2 (0.74) | POLBATMKMT2AADRB2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973936-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998046786-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC AMINOTHIOETHER ACIDS | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |