Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.58 |
| ▸ | FPR2 | P25090 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 2/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8093691 | 0.99 | ITGB3 (0.57) | ITGB3ITGA2BFPR2LMNALIPE | |
| SCHEMBL7444447 | 0.93 | ITGB3 (0.62) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7446594 | 0.91 | ITGB3 (0.61) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7447020 | 0.90 | ITGB3 (0.73) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7446061 | 0.90 | ITGB3 (0.58) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7445987 | 0.89 | ITGB3 (0.58) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL7447015 | 0.89 | ITGB3 (0.72) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL8109424 | 0.89 | ITGB3 (0.66) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| SCHEMBL7442370 | 0.89 | ITGB3 (0.56) | ITGB3ITGA2BFPR2HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL8103427 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BFPR2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | claimed |
| US-6025358-A | Double prodrugs of potent GP IIb/IIIa antagonists | G. D. SEARLE & CO. (US) | 2000-02-15 | — | — | US | disclosed |