SCHEMBL8093724

SCHEMBL8093724

CCCCC1CCC(c2ccc(C(C)c3ccc(N)cc3)cc2)(c2ccc(C(C)c3ccc(N)cc3)cc2)CC1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CYP19A1 P11511 17/20 0.38
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8094248 0.96 CYP19A1 (0.39) ALDH1A1L3MBTL1CYP19A1
SCHEMBL8092713 0.95 CYP19A1 (0.40) ALDH1A1L3MBTL1CYP19A1
SCHEMBL8094400 0.95 CYP19A1 (0.40) ALDH1A1L3MBTL1CYP19A1
SCHEMBL8085485 0.95 CYP19A1 (0.40) ALDH1A1L3MBTL1CYP19A1
SCHEMBL8094373 0.95 CYP19A1 (0.40) ALDH1A1L3MBTL1CYP19A1
SCHEMBL8860423 0.95 CYP19A1 (0.40) ALDH1A1L3MBTL1CYP19A1
SCHEMBL8094662 0.95 CYP19A1 (0.40) ALDH1A1L3MBTL1CYP19A1
SCHEMBL8860824 0.95 CYP19A1 (0.40) ALDH1A1L3MBTL1CYP19A1
SCHEMBL8086686 0.92 ALDH1A1 (0.40) ALDH1A1L3MBTL1CYP19A1
SCHEMBL6368376 0.90 ALDH1A1 (0.46) ALDH1A1L3MBTL1CYP19A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708077-B1 Diamino compounds and methods for preparing them CHISSO CORP (JP) 2000-12-27 EP disclosed
US-5807961-A Polyamic acid, polyimide film and liquid crystal aligning film and liquid crystal display element using the formers CHISSO CORPORATION (JP) 1998-09-15 US disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed