Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.63 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.63 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.63 |
| ▸ | MMP2 | P08253 | 16/20 | 0.61 |
| ▸ | MMP13 | P45452 | 11/20 | 0.61 |
| ▸ | MMP9 | P14780 | 9/20 | 0.61 |
| ▸ | MMP3 | P08254 | 8/20 | 0.61 |
| ▸ | MMP1 | P03956 | 7/20 | 0.61 |
| ▸ | MMP8 | P22894 | 3/20 | 0.59 |
| ▸ | MMP7 | P09237 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7653482 | 0.99 | SLC1A3 (0.61) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL7444501 | 0.89 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL7444497 | 0.89 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL13571156 | 0.87 | MMP2 (0.60) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL13571241 | 0.87 | MMP2 (0.60) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL13570945 | 0.87 | MMP2 (0.60) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL4621504 | 0.87 | MMP2 (0.66) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL4619626 | 0.87 | MMP2 (0.66) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL13570807 | 0.87 | MMP2 (0.62) | SLC1A3SLC1A2SLC1A1MMP2MMP13 | |
| SCHEMBL13570499 | 0.87 | MMP2 (0.62) | SLC1A3SLC1A2SLC1A1MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051625-A1 | ASSESSING RISK FOR INTEGRIN ANTAGONIST/AGONIST MEDIATED DISEASES | Du Pont Pharmaceuticals Company (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999038014-A1 | ASSESSING RISK FOR INTEGRIN ANTAGONIST/AGONIST MEDIATED DISEASES | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-07-29 | — | — | WO | disclosed |