Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088738 | 1.00 | TRPA1 (0.38) | TRPA1TRPM8MAPT | |
| SCHEMBL8183431 | 1.00 | TRPA1 (0.38) | TRPA1TRPM8MAPT | |
| SCHEMBL17675803 | 0.79 | — | — | |
| (-)-(1S,3R,4S,6S)-6-Hydroxymenthol SCHEMBL7043768 | 0.74 | TRPA1 (0.52) | TRPA1TRPM8 | |
| SCHEMBL12166614 | 0.70 | TRPA1 (0.46) | TRPA1TRPM8 | |
| SCHEMBL6884434 | 0.68 | — | — | |
| SCHEMBL6883369 | 0.68 | — | — | |
| SCHEMBL6757980 | 0.68 | — | — | |
| SCHEMBL6757966 | 0.68 | — | — | |
| SCHEMBL6758020 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6162932-A | Stereoselective synthesis of endothelin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-12-19 | — | — | US | disclosed |