Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR5 | P32302 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387179 | 0.93 | ALDH1A1 (0.41) | CXCR5ALDH1A1ALOX15CA2CYP3A4 | |
| SCHEMBL8102300 | 0.90 | ALDH1A1 (0.46) | ALDH1A1ALOX15CA2CYP3A4PRSS1 | |
| SCHEMBL8102325 | 0.90 | ALDH1A1 (0.44) | ALDH1A1ALOX15CA2CYP3A4TP53 | |
| SCHEMBL8087271 | 0.89 | PRSS1 (0.46) | ALDH1A1CA2CYP3A4PRSS1PRSS2 | |
| SCHEMBL30522478 | 0.89 | PRSS1 (0.46) | ALDH1A1CA2CYP3A4PRSS1PRSS2 | |
| SCHEMBL2386406 | 0.87 | CYSLTR2 (0.45) | ALDH1A1ALOX15CA2CYP3A4PRSS1 | |
| SCHEMBL269398 | 0.86 | CYSLTR2 (0.47) | ALDH1A1CA2CYP3A4PRSS1PRSS2 | |
| SCHEMBL6876901 | 0.85 | POLB (0.44) | CXCR5ALDH1A1ALOX15CA2CYP3A4 | |
| SCHEMBL8100822 | 0.84 | HTT (0.35) | ALDH1A1ALOX15CA2CYP3A4PRSS1 | |
| SCHEMBL8098022 | 0.83 | CXCR5 (0.38) | CXCR5ALDH1A1CA2CYP3A4PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143939-A1 | GLUCAN DERIVATIVE AND PREPARATION METHOD THEREFOR, AND ADDITIVE USED FOR PREPARING MEDICINE | 上海图珐医药科技有限公司 | 2021-07-22 | — | — | WO | disclosed |
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-5153218-A | N,N',N'-trisubstituted-bis-amino-3-methylene-2,4(3H,5H)-furandione inhibitors of acyl-CoA:cholesterol-acyl transferase | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |