SCHEMBL8094415

SCHEMBL8094415

CCCC1CCC(c2ccc(C(C)c3ccc(N)cc3C)cc2)(c2ccc(C(C)c3ccc(N)cc3C)cc2)CC1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8101932 0.93 CYP19A1 (0.31) CYP19A1
SCHEMBL8099950 0.92 CYP19A1 (0.32) CYP19A1
SCHEMBL8098969 0.92 ALDH1A1 (0.33) RXRAALDH1A1L3MBTL1CYP19A1
SCHEMBL8100386 0.91 CYP19A1 (0.33) CYP19A1
SCHEMBL8094099 0.91 CYP19A1 (0.33) CYP19A1
SCHEMBL8099943 0.91 CYP19A1 (0.33) CYP19A1
SCHEMBL8093897 0.91 CYP19A1 (0.33) CYP19A1
SCHEMBL8101606 0.91 CYP19A1 (0.33) CYP19A1
SCHEMBL8093879 0.91 CYP19A1 (0.33) CYP19A1
SCHEMBL8095246 0.91 CYP19A1 (0.33) CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708077-B1 Diamino compounds and methods for preparing them CHISSO CORP (JP) 2000-12-27 EP disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed