Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 1.00 |
| ▸ | OPRL1 | P41146 | 5/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 3/20 | 1.00 |
| ▸ | OPRD1 | P41143 | 2/20 | 1.00 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.63 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.62 |
| ▸ | PDE6D | O43924 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895708 | 0.88 | OPRM1 (0.79) | OPRM1OPRL1OPRK1OPRD1SLC6A9 | |
| SCHEMBL6839338 | 0.81 | SLC18A3 (0.74) | OPRM1OPRL1OPRK1OPRD1SLC18A3 | |
| SCHEMBL6839077 | 0.81 | SLC18A3 (0.74) | OPRM1OPRL1OPRK1OPRD1SLC18A3 | |
| Hydrochloric Acid SCHEMBL7706463 | 0.81 | SLC18A3 (0.72) | OPRM1OPRL1OPRK1OPRD1SLC18A3 | |
| Hydrochloric Acid SCHEMBL7706374 | 0.81 | SLC18A3 (0.72) | OPRM1OPRL1OPRK1OPRD1SLC18A3 | |
| Hydrochloric Acid SCHEMBL7703755 | 0.81 | SLC18A3 (0.72) | OPRM1OPRL1OPRK1OPRD1SLC18A3 | |
| Hydrochloric Acid SCHEMBL7703785 | 0.81 | SLC18A3 (0.72) | OPRM1OPRL1OPRK1OPRD1SLC18A3 | |
| Hydrochloric Acid SCHEMBL7709447 | 0.81 | SLC18A3 (0.72) | OPRM1OPRL1OPRK1OPRD1SLC18A3 | |
| Hydrochloric Acid SCHEMBL7709374 | 0.81 | SLC18A3 (0.72) | OPRM1OPRL1OPRK1OPRD1SLC18A3 | |
| Hydrochloric Acid SCHEMBL7706445 | 0.81 | SLC18A3 (0.72) | OPRM1OPRL1OPRK1OPRD1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000169476-A | 4-OXOIMIDAZOLIDINE-5-SPIRO-NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | BANYU PHARMACEUT CO LTD | 2000-06-20 | — | — | JP | disclosed |