Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809474 | 0.82 | HPGD (0.36) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL1453180 | 0.79 | MAPT (0.38) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL1107766 | 0.72 | MAPT (0.45) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL575613 | 0.72 | HSD17B10 (0.45) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Fluoride SCHEMBL777953 | 0.70 | HSD17B10 (0.43) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| Fluoride SCHEMBL1335636 | 0.70 | HSD17B10 (0.43) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL1111636 | 0.69 | HPGD (0.41) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL21011381 | 0.69 | MAPT (0.41) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL19622359 | 0.69 | MAPT (0.41) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL7529152 | 0.69 | MAPT (0.41) | HPGDMAPTSMN1; SMN2MGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968734-B2 | Organocatalysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-06-28 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | SCO2, CBR1, CBR3 | HPGD 868/4885MAPT 4442/4885SMN1; SMN2 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.