Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087566 | 0.90 | ALDH1A1 (0.43) | POLBTSHRKMT2AL3MBTL1KDM4E | |
| SCHEMBL8099853 | 0.89 | ALDH1A1 (0.46) | POLBTSHRL3MBTL1ALDH1A1TP53 | |
| SCHEMBL8094356 | 0.87 | ALDH1A1 (0.48) | TSHRKMT2AALDH1A1TP53MEN1 | |
| SCHEMBL8095842 | 0.86 | TSHR (0.55) | TSHRKMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL8085931 | 0.85 | POLB (0.40) | POLBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL6859419 | 0.84 | KMT2A (0.47) | POLBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL1481893 | 0.83 | PTPN1 (0.44) | POLBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL8096204 | 0.83 | HTT (0.38) | POLBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL1003281 | 0.83 | HTT (0.46) | POLBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL8102570 | 0.83 | SMN1; SMN2 (0.42) | POLBTSHRKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |