SCHEMBL809549

SCHEMBL809549

c1ccc(Nc2ccc(NC3CCCCCCCCCCC3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
GAA P10253 4/20 0.58
LMNA P02545 3/20 0.58
MAPK1 P28482 3/20 0.58
TDP1 Q9NUW8 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
ALDH1A1 P00352 3/20 0.53
ALOX15 P16050 2/20 0.53
ALOX12 P18054 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
PKM P14618 1/20 0.53
RAD52 P43351 1/20 0.53
GFER P55789 1/20 0.53
NPY5R Q15761 1/20 0.53
HSD17B10 Q99714 3/20 0.52
TSHR P16473 1/20 0.52
PTGS1 P23219 1/20 0.52
SLC6A2 P23975 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11356806 1.00 MAPT (0.58) MAPTMEN1KMT2AGAALMNA
SCHEMBL39716 1.00 MAPT (0.58) MAPTMEN1KMT2AGAALMNA
SCHEMBL809612 1.00 MAPT (0.58) MAPTMEN1KMT2AGAALMNA
SCHEMBL9514274 1.00 MAPT (0.58) MAPTMEN1KMT2AGAALMNA
SCHEMBL1848681 1.00 MAPT (0.58) MAPTMEN1KMT2AGAALMNA
Hydrochloric Acid SCHEMBL23089912 0.98 MAPT (0.57) MAPTMEN1KMT2AGAALMNA
SCHEMBL809415 0.98 MAPT (0.56) MAPTMEN1KMT2AGAALMNA
SCHEMBL24198978 0.92 KDM4E (0.53) MAPTMEN1KMT2AGAALMNA
SCHEMBL9934529 0.92 MAPT (0.55) MAPTMEN1KMT2AGAALMNA
SCHEMBL24514268 0.92 KDM4E (0.53) MAPTMEN1KMT2AGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8062551-B2 Antiozonant blends CHEMTURA CORPORATION (US) 2011-11-22 US claimed
EP-2013273-B1 ANTIOZONANT BLENDS CHEMTURA CORP (US) 2011-11-16 EP claimed
WO-2011130994-A1 MULTI-USER CHANNEL ESTIMATION METHOD AND DEVICE 中兴通讯股份有限公司 (CN) 2011-10-27 WO claimed
EP-2013273-A1 ANTIOZONANT BLENDS CHEMTURA CORPORATION (US) 2009-01-14 EP claimed
WO-2007130262-A1 ANTIOZONANT BLENDS CHEMTURA CORPORATION (US) 2007-11-15 WO claimed
US-20070260000-A1 Antiozonant blends ADDIVANT USA, LLC 2007-11-08 US claimed
US-8062551-B2 Antiozonant blends CHEMTURA CORPORATION (US) 2011-11-22 US disclosed
EP-2013273-B1 ANTIOZONANT BLENDS CHEMTURA CORP (US) 2011-11-16 EP disclosed
WO-2011130994-A1 MULTI-USER CHANNEL ESTIMATION METHOD AND DEVICE 中兴通讯股份有限公司 (CN) 2011-10-27 WO disclosed
EP-2013273-A1 ANTIOZONANT BLENDS CHEMTURA CORPORATION (US) 2009-01-14 EP disclosed
WO-2007130262-A1 ANTIOZONANT BLENDS CHEMTURA CORPORATION (US) 2007-11-15 WO disclosed
US-20070260000-A1 Antiozonant blends ADDIVANT USA, LLC 2007-11-08 US disclosed