Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400048 | 0.93 | MAPT (0.61) | MAPTLMNAGAAPOLBMEN1 | |
| SCHEMBL78145 | 0.93 | MAPT (0.61) | MAPTLMNAGAAPOLBMEN1 | |
| SCHEMBL11526941 | 0.93 | MAPT (0.61) | MAPTLMNAGAAPOLBMEN1 | |
| SCHEMBL9514274 | 0.92 | MAPT (0.58) | MAPTLMNAGAAPOLBMEN1 | |
| SCHEMBL39716 | 0.92 | MAPT (0.58) | MAPTLMNAGAAPOLBMEN1 | |
| SCHEMBL809612 | 0.92 | MAPT (0.58) | MAPTLMNAGAAPOLBMEN1 | |
| SCHEMBL1848681 | 0.92 | MAPT (0.58) | MAPTLMNAGAAPOLBMEN1 | |
| SCHEMBL11356806 | 0.92 | MAPT (0.58) | MAPTLMNAGAAPOLBMEN1 | |
| SCHEMBL809549 | 0.92 | MAPT (0.58) | MAPTLMNAGAAPOLBMEN1 | |
| SCHEMBL11526739 | 0.90 | MAPT (0.63) | MAPTLMNAGAAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835687-B2 | Method for preparation of 4,4′-dinitrodiphenylamine and 4,4′-bis(alkylamino)diphenylamine with the base catalyst complex | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2014-09-16 | — | — | US | disclosed |
| US-8759587-B2 | Method for preparation of 4,4′-dinitrodiphenylamine and 4,4′-bis(alkylamino)diphenylamine by using 4-nitroaniline | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2014-06-24 | — | — | US | disclosed |
| US-20120197044-A1 | PRODUCTION METHOD FOR 4,4'-BIS(ALKYLAMINO) DIPHENYLAMINE | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-08-02 | — | — | US | disclosed |
| US-20120157713-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE WITH THE BASE CATALYST COMPLEX | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-06-21 | — | — | US | disclosed |
| US-20120157714-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE BY USING 4-NITROANILINE | KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120157714-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE BY USING 4-NITROANILINE | NAAA, AADAT, HPD | MAPT 3922/4885LMNA 1694/4885GAA 1352/4885 |
| US-20120157713-A1 | METHOD FOR PREPARATION OF 4,4'-DINITRODIPHENYLAMINE AND 4,4'-BIS(ALKYLAMINO)DIPHENYLAMINE WITH THE BASE CATALYST COMPLEX | NAAA, HNF4A, ABAT | MAPT 2789/4885LMNA 1523/4885GAA 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.