Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2153533 | 0.85 | ALDH1A1 (0.50) | ALDH1A1ALOX15TSHRGABRA1GABRB2 | |
| SCHEMBL6905434 | 0.82 | ALDH1A1 (0.47) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL3140498 | 0.80 | IRAK4 (0.50) | ALDH1A1TSHRIRAK4HTTGAA | |
| SCHEMBL8100959 | 0.80 | ALDH1A1 (0.36) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL10627679 | 0.80 | ALDH1A1 (0.45) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL8087556 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ALOX15TSHRHTTKMT2A | |
| SCHEMBL8087127 | 0.77 | TSHR (0.55) | ALDH1A1ALOX15TSHRGABRA1GABRB2 | |
| SCHEMBL4667818 | 0.77 | ALDH1A1 (0.50) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL1882897 | 0.76 | ALDH1A1 (0.41) | ALDH1A1ALOX15TSHRCES2CES1 | |
| SCHEMBL8094230 | 0.75 | ALDH1A1 (0.38) | ALDH1A1ALOX15TSHRHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |