SCHEMBL8095527

SCHEMBL8095527

CCc1cc(Cc2ccc(CCc3ccc(Cc4ccc(N)c(CC)c4)cc3)cc2)ccc1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
MAPT P10636 3/20 0.44
GAA P10253 3/20 0.44
KDM4E B2RXH2 2/20 0.44
POLB P06746 2/20 0.44
CYP3A4 P08684 2/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
RAB9A P51151 1/20 0.44
CDC25B P30305 1/20 0.43
CASP6 P55212 1/20 0.43
RCE1 Q9Y256 1/20 0.43
TSHR P16473 2/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
HSD17B10 Q99714 1/20 0.42
BACE1 P56817 1/20 0.41
DHFR P00374 1/20 0.41
GFER P55789 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8094431 0.93 SKP2 (0.43) ALDH1A1MAPTGAAKDM4EPOLB
SCHEMBL8095465 0.93 SKP2 (0.43) ALDH1A1MAPTGAAKDM4EPOLB
SCHEMBL237448 0.92 ALDH1A1 (0.50) ALDH1A1MAPTGAAKDM4EPOLB
SCHEMBL8102159 0.91 SKP2 (0.42) ALDH1A1MAPTGAAKDM4EPOLB
SCHEMBL8102269 0.91 SKP2 (0.42) ALDH1A1MAPTGAAKDM4EPOLB
SCHEMBL8095809 0.91 SKP2 (0.42) ALDH1A1MAPTGAAKDM4EPOLB
SCHEMBL8085905 0.91 SKP2 (0.42) ALDH1A1MAPTGAAKDM4EPOLB
SCHEMBL8101910 0.91 SKP2 (0.42) ALDH1A1MAPTGAAKDM4EPOLB
SCHEMBL8100107 0.91 SKP2 (0.42) ALDH1A1MAPTGAAKDM4EPOLB
SCHEMBL8093157 0.91 SKP2 (0.42) ALDH1A1MAPTGAAKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708077-B1 Diamino compounds and methods for preparing them CHISSO CORP (JP) 2000-12-27 EP disclosed
US-5807961-A Polyamic acid, polyimide film and liquid crystal aligning film and liquid crystal display element using the formers CHISSO CORPORATION (JP) 1998-09-15 US disclosed
US-5663440-A Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1997-09-02 US disclosed
EP-0708077-A1 Diamino compounds and methods for preparing them CHISSO CORPORATION (JP) 1996-04-24 EP disclosed