SCHEMBL809556

SCHEMBL809556

CCOC(=O)C(C)[C@@H]1CC2(CCC1=O)OCCO2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.38
ALDH1A1 P00352 6/20 0.37
CYP3A4 P08684 3/20 0.37
CYP2C19 P33261 3/20 0.37
CYP2C9 P11712 1/20 0.37
POLB P06746 1/20 0.34
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33
GABRE P78334 1/20 0.33
GABRA6 Q16445 1/20 0.33
GABRG1 Q8N1C3 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2995029 0.77 TLR4 (0.39) ALDH1A1CYP3A4CYP2C19CYP2C9POLB
SCHEMBL30727078 0.77 TLR4 (0.39) ALDH1A1CYP3A4CYP2C19CYP2C9POLB
SCHEMBL12524744 0.77 POLB (0.31) POLBHSD11B1
SCHEMBL14506076 0.75 KMT2A (0.43) CYP2D6ALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL14533394 0.75 KMT2A (0.43) CYP2D6ALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL31013161 0.75 ALDH1A1 (0.38) CYP2D6ALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL31013030 0.75 ALDH1A1 (0.38) CYP2D6ALDH1A1CYP3A4CYP2C19CYP2C9
SCHEMBL182497 0.75 ALDH1A1 (0.36) ALDH1A1CYP3A4CYP2C19CYP2C9POLB
SCHEMBL809417 0.73 CYP2D6 (0.42) CYP2D6ALDH1A1CYP3A4CYP2C19POLB
SCHEMBL2360053 0.72 SLC6A2 (0.34) ALDH1A1CYP3A4CYP2C19CYP2C9POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968734-B2 Organocatalysts and methods of use in chemical synthesis STC.UNM (US) 2011-06-28 US disclosed
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis STC.UNM (US) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis SCO2, CBR1, CBR3 CYP2D6 193/4885ALDH1A1 1287/4885CYP3A4 231/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.