Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.70 |
| ▸ | MAPT | P10636 | 7/20 | 0.70 |
| ▸ | GAA | P10253 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.70 |
| ▸ | ALPG | P10696 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10950874 | 0.87 | MAPT (0.68) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL7821211 | 0.86 | MAPT (0.64) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL10954956 | 0.80 | MAPT (0.62) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL11499699 | 0.78 | MAPT (0.58) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL413498 | 0.78 | MAPT (0.56) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL20256177 | 0.78 | MAPT (0.55) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL2495266 | 0.76 | MAPT (0.54) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL1193562 | 0.75 | MEN1 (0.47) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL875772 | 0.74 | PDE7A (0.78) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL224666 | 0.74 | PDE7A (0.60) | ALDH1A1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-101018764-B | Process for synthesis of 4-4'-diamino-diphenyl-sulfone | LUNDBECK PHARMACEUTICALS ITALY | 2010-06-16 | — | — | CN | disclosed |
| CN-101018764-A | Process for synthesis of 4-4'-diamino-diphenyl-sulfone | LUNDBECK PHARMACEUTICALS ITALY (IT) | 2007-08-15 | — | — | CN | disclosed |
| EP-1042278-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | Slovakofarma, A.S. (SK) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032437-A1 | 1,3-DISUBSTITUTED UREAS AS ACAT INHIBITORS, AND METHOD OF PREPARING THEREOF | SLOVAKOFARMA, A.S. (SK) | 1999-07-01 | — | — | WO | disclosed |