Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.57 |
| ▸ | TNKS | O95271 | 1/20 | 0.57 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.57 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095715 | 1.00 | NPSR1 (0.64) | NPSR1KDM4EALDH1A1PKMHDAC4 | |
| Hydrochloric Acid SCHEMBL3939502 | 0.98 | NPSR1 (0.62) | NPSR1KDM4EALDH1A1PKMHDAC4 | |
| Hydrochloric Acid SCHEMBL3939500 | 0.98 | NPSR1 (0.62) | NPSR1KDM4EALDH1A1PKMHDAC4 | |
| SCHEMBL27573363 | 0.90 | NPSR1 (0.57) | NPSR1KDM4EALDH1A1PKMHDAC4 | |
| SCHEMBL27676665 | 0.88 | NPSR1 (0.49) | NPSR1KDM4EALDH1A1PKMHDAC4 | |
| SCHEMBL19313214 | 0.88 | NPSR1 (0.49) | NPSR1KDM4EALDH1A1PKMHDAC4 | |
| SCHEMBL27789579 | 0.86 | NPSR1 (0.60) | NPSR1KDM4EALDH1A1PKMHDAC4 | |
| SCHEMBL28301215 | 0.85 | MAOB (0.62) | PKMHDAC4HDAC3HDAC1HDAC7 | |
| SCHEMBL853486 | 0.84 | NPSR1 (0.61) | NPSR1KDM4EALDH1A1PKMHDAC4 | |
| SCHEMBL853485 | 0.84 | NPSR1 (0.61) | NPSR1KDM4EALDH1A1PKMHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101535232-B | Fragrance compound | GIVAUDAN S.A. (CH) | 2016-05-11 | — | — | CN | disclosed |
| EP-0716661-B1 | PSEUDO- AND NON-PEPTIDE BRADYKININ RECEPTOR ANTAGONISTS | SCIOS INC (US) | 2000-04-05 | — | — | EP | disclosed |
| US-5541286-A | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids | SCIOS NOVA INC. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0716661-A1 | PSEUDO- AND NON-PEPTIDE BRADYKININ RECEPTOR ANTAGONISTS | SCIOS NOVA INC. (US) | 1996-06-19 | — | — | EP | disclosed |
| US-5444048-A | Antiinflammatory agents, analgesics | SCIOS NOVA, INC. (US) | 1995-08-22 | — | — | US | disclosed |
| WO-1995007294-A1 | PSEUDO- AND NON-PEPTIDE BRADYKININ RECEPTOR ANTAGONISTS | SCIOS NOVA INC. (US) | 1995-03-16 | — | — | WO | disclosed |