Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676665 | 1.00 | NPSR1 (0.49) | NPSR1PTGS1PTGS2PKMKDM4E | |
| SCHEMBL8095713 | 0.88 | NPSR1 (0.64) | NPSR1PKMKDM4EALDH1A1ENPP2 | |
| SCHEMBL8095715 | 0.88 | NPSR1 (0.64) | NPSR1PKMKDM4EALDH1A1ENPP2 | |
| Hydrochloric Acid SCHEMBL3939502 | 0.86 | NPSR1 (0.62) | NPSR1PKMKDM4EALDH1A1HDAC4 | |
| SCHEMBL15026335 | 0.86 | NPSR1 (0.49) | NPSR1PTGS1PTGS2PKMKDM4E | |
| Hydrochloric Acid SCHEMBL3939500 | 0.86 | NPSR1 (0.62) | NPSR1PKMKDM4EALDH1A1HDAC4 | |
| SCHEMBL44581 | 0.85 | PTGS2 (0.59) | NPSR1PTGS1PTGS2PKMKDM4E | |
| SCHEMBL44580 | 0.85 | PTGS2 (0.59) | NPSR1PTGS1PTGS2PKMKDM4E | |
| SCHEMBL27521629 | 0.84 | HDAC2 (0.50) | NPSR1PTGS1PTGS2HDAC1HDAC8 | |
| SCHEMBL27521632 | 0.84 | HDAC2 (0.50) | NPSR1PTGS1PTGS2HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2809657-B1 | NOVEL THERAPEUTIC AGENTS | EURO CELTIQUE SA (LU) | 2017-09-06 | — | — | EP | disclosed |