Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | F13A1 | P00488 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695548 | 1.00 | LMNA (0.48) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL4522860 | 1.00 | LMNA (0.48) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9694437 | 1.00 | LMNA (0.48) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL8087407 | 0.98 | LMNA (0.49) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL8095483 | 0.94 | CYP1A2 (0.50) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9695748 | 0.82 | LMNA (0.44) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL9694448 | 0.81 | CYP1A2 (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL19379585 | 0.81 | CYP1A2 (0.46) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| SCHEMBL10495784 | 0.80 | F13A1 (0.40) | LMNACYP2C9CHRM1TBXA2RPDE4A | |
| Adipic Acid SCHEMBL11592222 | 0.78 | TSHR (0.53) | LMNACYP2C9CHRM1TBXA2RPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103216-A | POLYHALOGENATED TRIGLYCERIDES, SUCH AS 2-OLEOYLGLYCEROL-1,3-BIS(7-(3-AMINO-2,4,6-TRIIODOPHENYL)HEPTAN OATE) OR 2-OLEOYLGLYCEROL-1,3-BIS(.OMEGA.-(3,5-BIS-TRIFLUOROMETHYL)-HEP | THE BOARD OF REGENTS ACTING FOR AND ON BEHALF OF THE UNIVERSITY OF MICHIGAN (US) | 2000-08-15 | — | — | US | disclosed |