Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099846 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1KCNH2LMNAMAPT | |
| SCHEMBL8095927 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TDP1KCNH2LMNAMAPT | |
| SCHEMBL8092479 | 0.99 | ALDH1A1 (0.49) | ALDH1A1TDP1KCNH2LMNAMAPT | |
| SCHEMBL8086182 | 0.94 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNAMAPTHTT | |
| SCHEMBL8102317 | 0.89 | KMT2A (0.45) | ALDH1A1TDP1LMNAMAPTHTT | |
| SCHEMBL8094160 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TDP1KCNH2MGLLCYP19A1 | |
| SCHEMBL7207882 | 0.86 | KMT2A (0.51) | ALDH1A1TDP1KCNH2MGLLCYP19A1 | |
| SCHEMBL8094302 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TDP1KCNH2MGLLCYP19A1 | |
| SCHEMBL8102118 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TDP1KCNH2MGLLCYP19A1 | |
| SCHEMBL11615752 | 0.86 | KMT2A (0.51) | ALDH1A1TDP1KCNH2MGLLCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |