Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.48 |
| ▸ | CNR1 | P21554 | 6/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100945 | 0.98 | CNR2 (0.47) | CNR2CNR1GPR55LIPGTLR8 | |
| SCHEMBL8094984 | 0.98 | CNR2 (0.47) | CNR2CNR1GPR55LIPGTLR8 | |
| SCHEMBL8101600 | 0.98 | CNR2 (0.47) | CNR2CNR1GPR55LIPGTLR8 | |
| SCHEMBL8100912 | 0.95 | CNR1 (0.43) | CNR2CNR1GPR55LIPGTLR8 | |
| SCHEMBL8099932 | 0.94 | TLR8 (0.47) | CNR2CNR1GPR55LIPGTLR8 | |
| SCHEMBL8100554 | 0.93 | TLR8 (0.46) | CNR2CNR1GPR55LIPGTLR8 | |
| SCHEMBL8094286 | 0.93 | TLR8 (0.46) | CNR2CNR1GPR55LIPGTLR8 | |
| SCHEMBL8099971 | 0.93 | TLR8 (0.46) | CNR2CNR1GPR55LIPGTLR8 | |
| SCHEMBL8102088 | 0.89 | TLR8 (0.42) | CNR2CNR1GPR55TLR8HTT | |
| SCHEMBL8093886 | 0.89 | TAAR1 (0.40) | CNR2CNR1GPR55TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |