Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096701 | 0.93 | HTR2A (0.43) | TAAR1LTA4HCNR2CNR1LDHA | |
| SCHEMBL8100912 | 0.90 | CNR1 (0.43) | TAAR1CNR2CNR1SLC6A2SLC6A4 | |
| SCHEMBL8096090 | 0.89 | CNR2 (0.48) | TAAR1CNR2CNR1GPR55 | |
| SCHEMBL8101600 | 0.87 | CNR2 (0.47) | CNR2CNR1GPR55 | |
| SCHEMBL8100945 | 0.87 | CNR2 (0.47) | CNR2CNR1GPR55 | |
| SCHEMBL8094984 | 0.87 | CNR2 (0.47) | CNR2CNR1GPR55 | |
| SCHEMBL8100277 | 0.86 | DHFR (0.43) | TAAR1LTA4HCNR2CNR1SLC6A2 | |
| SCHEMBL8101085 | 0.85 | LTA4H (0.47) | TAAR1LTA4HCNR2CNR1SLC6A2 | |
| SCHEMBL6546756 | 0.85 | TAAR1 (0.48) | TAAR1LTA4HCNR2CNR1GPR55 | |
| SCHEMBL8102088 | 0.84 | TLR8 (0.42) | CNR2CNR1GPR55LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |