SCHEMBL809631

SCHEMBL809631

C=CC(=O)NC(C)C=C.C=CCNC(=O)C=C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
ALDH1A1 P00352 3/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
RAB9A P51151 2/20 0.41
NPC1 O15118 1/20 0.41
MAPT P10636 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
KMT2A Q03164 1/20 0.35
FAAH O00519 1/20 0.35
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ATM Q13315 1/20 0.33
ALPL P05186 1/20 0.32
PKM P14618 1/20 0.32
ACACB O00763 1/20 0.31
CYP2C19 P33261 1/20 0.31
TGM2 P21980 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125983 0.84
SCHEMBL30851 0.80
Urea SCHEMBL1782560 0.79 TSHR (0.58) TSHRALDH1A1MAPK1TDP1ZDHHC20
Dimethylamine SCHEMBL3821887 0.78 TSHR (0.54) TSHRALDH1A1MAPK1TDP1SMN1; SMN2
Methane SCHEMBL27388128 0.78
Ammonia Solution, Strong SCHEMBL1076016 0.78
Charcoal, Activated SCHEMBL890031 0.78
Trimethylammonium SCHEMBL28033781 0.77 TSHR (0.52) TSHRALDH1A1MAPK1TDP1SMN1; SMN2
SCHEMBL11874311 0.76 TSHR (0.56) TSHRALDH1A1MAPK1TDP1SMN1; SMN2
SCHEMBL20969217 0.73 TSHR (0.43) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3571348-B1 HIGH MOLECULAR WEIGHT TEMPORARY WET STRENGTH RESIN FOR PAPER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2024-03-06 EP disclosed
US-11028538-B2 Composition and method for increasing wet and dry paper strength SOLENIS TECHNOLOGIES, L.P. (US) 2021-06-08 US disclosed
US-10954633-B2 Process for making paper, paperboard or the like KEMIRA OYJ (FI) 2021-03-23 US disclosed
US-20200277735-A1 COMPOSITION AND METHOD FOR INCREASING WET AND DRY PAPER STRENGTH SOLENIS TECHNOLOGIES, L.P. (US) 2020-09-03 US disclosed
EP-3481994-B1 PROCESS FOR MAKING PAPER, PAPERBOARD OR THE LIKE KEMIRA OYJ (FI) 2020-04-15 EP disclosed
US-20180327974-A1 Process for making paper, paperboard or the like KEMIRA OYJ (FI) 2018-11-15 US disclosed
EP-3044365-B1 HIGH MOLECULAR WEIGHT AND HIGH CATIONIC CHARGEGLYOXALATEDPOLYACRYLAMIDE COPOLYMERS, AND THEIR METHODS OF MANUFACTURE AND USE BASF SE (DE) 2018-05-23 EP disclosed
EP-2788392-B1 PREPARATION OF POLYVINYLAMIDE CELLULOSE REACTIVE ADDUCTS BASF SE (DE) 2018-02-21 EP disclosed
US-9879381-B2 Preparation of polyvinylamide cellulose reactive adducts BASF SE (DE) 2018-01-30 US disclosed
US-20170159242-A9 Preparation of polyvinylamide cellulose reactive adducts THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2017-06-08 US disclosed
US-20110224374-A1 GLYOXALATED N-VINYLAMINE BASF SE (DE) 2011-09-15 US disclosed
EP-2343324-A1 Glyoxalated poly(n-vinylamine) BASF SE (DE) 2011-07-13 EP disclosed
US-20110083821-A1 GLYOXALATION OF VINYLAMIDE POLYMER THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2011-04-14 US disclosed
US-7875676-B2 Reacting substantially aqueous reaction mixture of a vinylamide polymer and a cellulose reactive agent to form the adduct,wherein concentration of vinylamide polymer is below, equal to or no more than 1% above a Critical Concentration of the vinylamide polymer; dry and wet strength aid for paper CIBA SPECIALTY CHEMICALS CORPORATION (US) 2011-01-25 US disclosed
US-20090223645-A1 Method and composition for improved temporary wet strength ZHANG NAIJIE 2009-09-10 US disclosed
US-20090126890-A1 Glyoxalated N-vinylamine THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2009-05-21 US disclosed
US-20080108533-A1 Methacrylate copolymer pour point depressants CIBA CORP. 2008-05-08 US disclosed
US-20080064819-A1 Glyoxalation of vinylamide polymer THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A., AS NOTES COLLATERAL AGENT 2008-03-13 US disclosed
EP-1828479-A1 HIGH-PERFORMANCE STRENGTH RESINS IN PAPERMAKING INDUSTRIES Lanxess Corporation (US) 2007-09-05 EP disclosed
WO-2006016906-A1 HIGH-PERFORMANCE STRENGTH RESINS IN PAPERMAKING INDUSTRIES LANXESS CORPORATION (US) 2006-02-16 WO disclosed