Urea

Urea

SCHEMBL1782560

C=CC(=O)NC(C)C=C.NC(N)=O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
ALDH1A1 P00352 4/20 0.36
FGFR4 P22455 1/20 0.36
CYP2C19 P33261 1/20 0.35
MAPK1 P28482 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ACACB O00763 2/20 0.32
TGM2 P21980 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125983 0.93
SCHEMBL20969217 0.85 TSHR (0.43) TSHR
SCHEMBL809631 0.79 TSHR (0.48) TSHRALDH1A1CYP2C19MAPK1TDP1
Urea SCHEMBL11159986 0.77 TSHR (0.50) TSHRALDH1A1FGFR4CYP2C19MAPK1
SCHEMBL29198729 0.77
SCHEMBL28681811 0.77 TSHR (0.56) TSHRALDH1A1FGFR4CYP2C19MAPK1
SCHEMBL20790352 0.76 TSHR (0.50) TSHRALDH1A1FGFR4CYP2C19MAPK1
SCHEMBL20790351 0.76 TSHR (0.50) TSHRALDH1A1FGFR4CYP2C19MAPK1
SCHEMBL8373316 0.76 TSHR (0.60) TSHRALDH1A1FGFR4CYP2C19MAPK1
Acrylamide SCHEMBL2429839 0.76 TSHR (0.82) TSHRALDH1A1FGFR4CYP2C19MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8500903-B2 Plaster-based material including an agent capable of trapping formaldehyde BPB LIMITED (GB) 2013-08-06 US claimed
EP-2327672-A1 Plaster-based material including an agent capable of trapping formaldehyde. BPB Limited (GB) 2011-06-01 EP claimed
WO-2011058172-A1 PLASTER-BASED MATERIAL INCLUDING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE BPB LIMITED (GB) 2011-05-19 WO claimed
US-20110113961-A1 PLASTER-BASED MATERIAL INCLUDING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE BPB LIMITED (GB) 2011-05-19 US claimed
CN-108431129-B Aqueous emulsion and adhesive obtained using same 株式会社可乐丽 2021-10-08 CN disclosed
CN-110753709-A Aqueous emulsion and adhesive using same 株式会社可乐丽 2020-02-04 CN disclosed
EP-3429976-A1 PLASTERBOARD Saint-Gobain Placo (FR) 2019-01-23 EP disclosed
US-9174870-B2 Plaster-based material including an agent capable of trapping formaldehyde BPB LIMITED (GB) 2015-11-03 US disclosed
US-20130276673-A1 PLASTER-BASED MATERIAL INCLUDING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE BPB LTD (GB) 2013-10-24 US disclosed
US-8500903-B2 Plaster-based material including an agent capable of trapping formaldehyde BPB LIMITED (GB) 2013-08-06 US disclosed
EP-2327672-A1 Plaster-based material including an agent capable of trapping formaldehyde. BPB Limited (GB) 2011-06-01 EP disclosed
WO-2011058172-A1 PLASTER-BASED MATERIAL INCLUDING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE BPB LIMITED (GB) 2011-05-19 WO disclosed
US-20110113961-A1 PLASTER-BASED MATERIAL INCLUDING AN AGENT CAPABLE OF TRAPPING FORMALDEHYDE BPB LIMITED (GB) 2011-05-19 US disclosed