Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.72 |
| ▸ | GBA1 | P04062 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.61 |
| ▸ | PDE5A | O76074 | 2/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.58 |
| ▸ | KDM1A | O60341 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201364 | 0.90 | ABCG2 (0.94) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL5531993 | 0.87 | ABCG2 (0.89) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL8095812 | 0.87 | ABCG2 (1.00) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL13968366 | 0.86 | ABCG2 (0.58) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL5527457 | 0.84 | ABCG2 (0.83) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL8093527 | 0.84 | ABCG2 (0.82) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL1083796 | 0.82 | KDM4E (1.00) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL8087337 | 0.81 | ABCG2 (0.85) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL2296472 | 0.79 | ABCG2 (0.74) | ABCG2MAPTTP53LMNAMEN1 | |
| SCHEMBL1063103 | 0.77 | ABCG2 (1.00) | ABCG2MAPTTP53LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000085-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES USEFUL AS MODULATORS OF GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2008-12-31 | — | — | WO | disclosed |