Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418367 | 0.94 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11662783 | 0.94 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9638004 | 0.92 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| SCHEMBL28268541 | 0.92 | TSHR (0.57) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| Acrylic Acid SCHEMBL8102270 | 0.91 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| Fumaric Acid SCHEMBL8095916 | 0.89 | HCAR2 (0.57) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| Maleic Acid SCHEMBL8095912 | 0.89 | HCAR2 (0.57) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| Methacrylic Acid SCHEMBL6054004 | 0.87 | ALDH1A1 (0.56) | HPGDALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL7852013 | 0.86 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4MAPK1 | |
| Styrene SCHEMBL8097086 | 0.86 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886065-A | WATERFASTNESS, NON-FLOCCULATING | HEWLETT-PACKARD COMPANY (US) | 1999-03-23 | — | — | US | claimed |
| US-6034153-A | STABLE COLORANT | HEWLETT-PACKARD COMPANY (US) | 2000-03-07 | — | — | US | disclosed |
| US-5886065-A | WATERFASTNESS, NON-FLOCCULATING | HEWLETT-PACKARD COMPANY (US) | 1999-03-23 | — | — | US | disclosed |