Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 18/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 18/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 17/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096891 | 1.00 | SLC1A2 (0.54) | SLC1A2SLC1A1SLC1A3MMP1MMP2 | |
| SCHEMBL8096888 | 1.00 | SLC1A2 (0.54) | SLC1A2SLC1A1SLC1A3MMP1MMP2 | |
| SCHEMBL4953255 | 0.84 | MMP1 (0.50) | SLC1A2SLC1A1SLC1A3MMP1MMP2 | |
| SCHEMBL19846200 | 0.84 | MMP1 (0.50) | SLC1A2SLC1A1SLC1A3MMP1MMP2 | |
| SCHEMBL13583919 | 0.79 | SLC7A5 (0.44) | SLC1A2SLC1A1SLC1A3MMP1MMP2 | |
| SCHEMBL13583918 | 0.79 | SLC7A5 (0.44) | SLC1A2SLC1A1SLC1A3MMP1MMP2 | |
| SCHEMBL12091193 | 0.78 | MMP1 (0.45) | SLC1A2SLC1A1SLC1A3MMP1MMP2 | |
| SCHEMBL6892557 | 0.78 | MMP1 (0.67) | SLC1A2SLC1A1SLC1A3MMP1MMP2 | |
| SCHEMBL19846192 | 0.77 | MMP1 (0.44) | SLC1A2SLC1A1SLC1A3MMP1MMP2 | |
| SCHEMBL19846183 | 0.77 | SLC1A3 (0.45) | SLC1A2SLC1A1SLC1A3MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147113-A | ADMINISTERING TO TREAT NERVOUS SYSTEM AND BRAIN DISORDERS; GLUTAMATE UPTAKE INHIBITORS | SUNTORY LIMITED (JP) | 2000-11-14 | — | — | US | disclosed |