SCHEMBL809694

SCHEMBL809694

O=C(c1ccc(Cl)cc1)c1ccc(Oc2ccc(C(c3ccc(Oc4ccc(C(=O)c5ccc(Cl)cc5)cc4)cc3)(C(F)(F)F)C(F)(F)F)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.51
ELANE P08246 1/20 0.49
PPARG P37231 2/20 0.48
PPARA Q07869 2/20 0.48
FABP2 P12104 1/20 0.48
SLC22A12 Q96S37 1/20 0.48
SRD5A2 P31213 3/20 0.44
MAPK1 P28482 2/20 0.44
MMP1 P03956 2/20 0.44
CYP11B1 P15538 1/20 0.43
CYP11B2 P19099 1/20 0.43
CYP3A4 P08684 2/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 2/20 0.43
MAPT P10636 2/20 0.43
USP2 O75604 1/20 0.43
ABCB11 O95342 1/20 0.43
CYP1A2 P05177 1/20 0.43
ADORA3 P0DMS8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2696709 0.93 MAPT (0.49) HPGDELANEPPARGPPARAFABP2
SCHEMBL2628120 0.93 HPGD (0.65) HPGDELANEPPARGPPARAFABP2
SCHEMBL14030884 0.93 MAPT (0.49) HPGDELANEPPARGPPARAFABP2
SCHEMBL12861248 0.92 HPGD (0.44) HPGDELANEPPARGPPARAFABP2
SCHEMBL14599492 0.91 ENPP1 (0.45) HPGDELANEPPARGPPARAFABP2
SCHEMBL14344270 0.88 HPGD (0.51) HPGDELANEPPARGPPARAFABP2
SCHEMBL14030818 0.85 HPGD (0.55) HPGDELANEMAPTSMN1; SMN2RAB9A
SCHEMBL12770267 0.85 HTT (0.46) HPGDELANEKMT2ALMNAMAPT
SCHEMBL13082190 0.85 HPGD (0.42) HPGDELANEPPARGPPARAFABP2
SCHEMBL14511013 0.84 MMP13 (0.53) HPGDELANESRD5A2MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8815465-B2 Membrane electrode assembly for polymer electrolyte fuel cell and polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2014-08-26 US disclosed
US-8399148-B2 Varnish for a solid polymer fuel cell JSR CORPORATION (JP) 2013-03-19 US disclosed
US-20120301809-A1 MEMBRANE ELECTRODE ASSEMBLY FOR POLYMER ELECTROLYTE FUEL CELL AND POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2012-11-29 US disclosed
US-8309678-B2 Aromatic compound and polyarylene copolymer having nitrogen-containing heterocycle including sulfonic acid group in side chain JSR CORPORATION (JP) 2012-11-13 US disclosed
US-8293905-B2 Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
US-20120251919-A1 POLYARYLENE-BASED COPOLYMER AND USES THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 US disclosed
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-8236920-B2 Polyarylene and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-08-07 US disclosed
EP-2112133-B1 Halogenated aromatic compound, polymer thereof, and proton-conductive membrane comprising same JSR CORP (JP) 2012-07-04 EP disclosed
EP-1693405-B1 PROTON CONDUCTING MEMBRANE AND PROCESS FOR PRODUCING THE SAME JSR CORP (JP) 2012-05-02 EP disclosed
EP-1400548-A1 Novel aromatic sulfonic acid ester derivative, polyarylene, polyarylene having sulfonic acid group and process for producing the same, and polymer solid electrolyte and proton-conductive membrane JSR Corporation (JP) 2004-03-24 EP disclosed
US-20040044166-A1 Novel aromatic sulfonic acid ester derivative, polyarylene, polyarylene having sulfonic acid group and process for producing the same, and polymer solid electrolyte and proton-conductive membrane JSR CORPORATION (JP) 2004-03-04 US disclosed
EP-1391480-A1 Proton conductive resin composition, method for preparing the same, and proton conductive membrane comprising the composition JSR Corporation (JP) 2004-02-25 EP disclosed
US-20040028806-A1 Process for producing electrolyte membrane-bonded electrode and varnish composition used therein THE RELIABLE AUTOMATIC SPRINKLER CO. INC. 2004-02-12 US disclosed
US-6685984-B2 FORMING FUEL CELL COMPRISED OF NONPENETRATING ELECTROLYTE MEMBRANE ON ELECTRODE JSR CORPORATION (JP) 2004-02-03 US disclosed
US-20030228421-A1 Method for the production of multilayers JSR CORPORATION 2003-12-11 US disclosed
US-20030173547-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR CORPORATION (JP) 2003-09-18 US disclosed
EP-1329444-A1 Halogenated aromatic compound, (co)polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2003-07-23 EP disclosed
US-20020188097-A1 Polyether ketone polymers provide stable mechanical and thermal properties (durability) when sulfonated; for use in batteries/fuel cells JSR CORPORATION (JP) 2002-12-12 US disclosed
EP-1245555-A1 Halogenated aromatic compound, polymer thereof, and proton-conductive membrane comprising same JSR Corporation (JP) 2002-10-02 EP disclosed