Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84317 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL22771576 | 0.91 | — | — | |
| SCHEMBL13920867 | 0.74 | — | — | |
| SCHEMBL387597 | 0.73 | — | — | |
| SCHEMBL794656 | 0.72 | KMT2A (0.62) | FNTAFNTBKMT2A | |
| SCHEMBL20879345 | 0.72 | KMT2A (0.62) | FNTAFNTBKMT2A | |
| SCHEMBL798172 | 0.72 | KMT2A (0.62) | FNTAFNTBKMT2A | |
| SCHEMBL433370 | 0.71 | KMT2A (0.35) | NOS1KMT2A | |
| SCHEMBL3951138 | 0.71 | KMT2A (0.67) | FNTAFNTBKMT2A | |
| SCHEMBL8461809 | 0.71 | KMT2A (0.67) | FNTAFNTBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057371-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, GASTROINTESTINAL DISORDERS, DRUG ABUSE, ANGINA, MIGRAINE, HYPERTENSION AND DEPRESSION | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0591426-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993000313-A2 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1993-01-07 | — | — | WO | disclosed |