SCHEMBL8097233

SCHEMBL8097233

CC(N)OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.43
CA1 P00915 5/20 0.37
CA2 P00918 5/20 0.37
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28348130 0.84 THRB (0.46) THRBCA1CA2MMP1MMP2
SCHEMBL9017955 0.84 THRB (0.46) THRBCA1CA2MMP1MMP2
SCHEMBL26101502 0.84 THRB (0.46) THRBCA1CA2MMP1MMP2
SCHEMBL28726936 0.84
SCHEMBL4455268 0.82 THRB (0.43) THRBCA1CA2MMP1MMP2
SCHEMBL26101283 0.75 TSHR (0.39) THRBCA1CA2MMP1MMP2
SCHEMBL359980 0.74 TSHR (0.31)
SCHEMBL27777783 0.73 THRB (0.36) THRBCA1CA2
SCHEMBL7125428 0.73 THRB (0.52) THRBCA1CA2F2PRSS1
SCHEMBL198030 0.73 THRB (0.52) THRBCA1CA2F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6132928-A Coating solution for forming antireflective coating film TOKYO OHKA KOGYO CO., LTD. (JP) 2000-10-17 US disclosed