Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 7/20 | 0.45 |
| ▸ | RPS6KA4 | O75676 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 9/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738350 | 0.77 | RPS6KA5 (0.46) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL3262202 | 0.75 | RPS6KA5 (0.53) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL256382 | 0.75 | RPS6KA5 (0.45) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL28849705 | 0.72 | RPS6KA5 (0.40) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL12775613 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL29114227 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL19250468 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL29114200 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL12844573 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL30662366 | 0.69 | RPS6KA5 (0.51) | RPS6KA5RPS6KA4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011120327-A1 | ANTI-TUMOR MEDICAMENT OF STRUCTURE OF DIARYLUREA OR THIOUREA KIND BASED ON INDAZOLE OR AZA-INDAZOLE | 济南海乐医药技术开发有限公司 (CN) | 2011-10-06 | — | — | WO | disclosed |
| JP-2000038388-A | PRODUCTION OF 5-ACYLAMINOPYOROPYRIMIDINE DERIVATIVE | FUJI PHOTO FILM CO LTD | 2000-02-08 | — | — | JP | disclosed |