Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 10/20 | 0.53 |
| ▸ | RPS6KA4 | O75676 | 4/20 | 0.49 |
| ▸ | EGFR | P00533 | 9/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738350 | 0.77 | RPS6KA5 (0.46) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL8097276 | 0.75 | RPS6KA5 (0.45) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL256382 | 0.75 | RPS6KA5 (0.45) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL28849705 | 0.72 | RPS6KA5 (0.40) | RPS6KA5RPS6KA4EGFRHDAC6 | |
| SCHEMBL29114200 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL12775613 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL12844573 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL19250468 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFR | |
| SCHEMBL29114227 | 0.71 | RPS6KA5 (0.42) | RPS6KA5RPS6KA4EGFRHDAC1HDAC6 | |
| SCHEMBL30662366 | 0.69 | RPS6KA5 (0.51) | RPS6KA5RPS6KA4EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160311-A1 | Fungicidal Azolopyrimidines, Process for Their Preparation and Their Use For Controlling Harmful Fungi, and Also Compositions Comprising Them | BASF SE (DE) | 2010-06-24 | — | — | US | disclosed |
| US-20100056371-A1 | Use of Azolopyrimidines for Controlling Phytopathogenic Harmful Fungi | BASF SE (DE) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056371-A1 | Use of Azolopyrimidines for Controlling Phytopathogenic Harmful Fungi | DPM1, TYMP, G6PD | RPS6KA5 1643/4885RPS6KA4 2187/4885EGFR 4557/4885 |
| US-20100160311-A1 | Fungicidal Azolopyrimidines, Process for Their Preparation and Their Use For Controlling Harmful Fungi, and Also Compositions Comprising Them | G6PD, CYP51A1, ERG28 | RPS6KA5 1940/4885RPS6KA4 2654/4885EGFR 4619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.